Holiday Inn Express St. Louis. Located on the doorstep of downtown in historic Lafayette Square, our St. Louis, MO hotel is close to the area's best sightseeing and businesses. 116 Rooms - Looking for a St. Louis hotel with well-appointed rooms. We provide outstanding amenities with free, high-speed Internet access, a microwave, refrigerator and a well-lit work desk with an ergonomic chair. Relax in a lounge chair while you watch your favorite shows on the flat screen TV Buffet Breakfast included, Continental Breakfast included Booking and cancellation policies vary by rate type. Please check all applicable rules prior to booking to avoid possible charges. American Disabilities Act. If your accessibility needs are not met, please contact the Hotel Manager on Duty. Should you require additional information regarding accessible facilities for guests with disabilities, please call 1-800-465-4329 (U.S. and Canada) or contact the hotel directly. For the hearing impaired, TDD service is available at 1-800-238-5544 within the U.S. and Canada